Research And Education
Advances And Recognitions
Overview For children with kidney disease and disorders, the Division of Pediatric Nephrology at Stony Brook Children's offers the most advanced treatment available in Suffolk County. We were ranked among the top 50 providers for nephrology in the 2014-15 Best Children's Hospitals rankings in U.S. News & World Report. Not only is it the only Suffolk County hospital to perform renal transplants for children, it also is home to one of the largest pediatric nephrology programs on Long Island, seeing approximately 1,400 patients annually.
Our Team Team members include physicians, a nurse practitioner, a dialysis nurse, and other medical professionals with pediatric nephrology expertise. The team works closely with other pediatric specialty departments at Stony Brook, in particular pediatric surgery, pediatric urology, and transplantation services, to provide state-of-the-art, compassionate and family-centered care.
Hypertension, or higher than normal blood pressure, is a growing problem in children, largely due to an increase in obesity and metabolic disorders. Hypertension is one of the most reliable predictors of future problems with the kidneys, in addition to raising a child’s risk for other serious health issues such cardiovascular disease.
To address pediatric hypertension, Stony Brook Children’s has launched the region’s first Pediatric Hypertension Center. Taking a multidisciplinary approach, the center brings pediatric specialists together to comprehensively address emerging or existing hypertension issues in children. In addition to family education, counseling and lifestyle and medical management, the center uses ambulatory blood pressure monitoring to track blood pressure changes for 24 hours. The information obtained by the monitor helps doctors develop an individualized program addressing each patient’s needs.
Transplants. Close to 70 adult and pediatric kidney transplants are performed at Stony Brook Medicine annually with excellent immediate surgical and long-term results. Most transplant recipients can expect to lead normal, healthy lives after surgery. At Stony Brook, the success rate of the new kidney function in pediatric patients is 100 percent after one year.
Treatment for Chronic and Acute Conditions. For chronic and acute kidney conditions, including nephritis, nephrosis and nephrotic syndrome, renal artery stenosis and renal failure, Stony Brook offers a number of options.
Patient Resources Stony Brook is the only hospital in New York to host a chapter of NephCure, a nationwide organization dedicated to sharing resources, educating, and supporting children and families with nephrotic syndrome. For information, call (631) 444-7884.
Research and Education As Suffolk County's only academic medical center, Stony Brook is committed to training the next generation of physicians. Six to 12 residents a year rotate through the Division of Pediatric Nephrology, not only gaining valuable experience in state-of-the-art medicine, but also continually infusing the program with the latest ideas and approaches.
On the research front, Stony Brook participates in numerous studies, allowing patients who qualify access to the novel therapies and approaches only available in clinical trials. Currently, the department is involved in a multi-center, randomized, double-blind, active-control, dose-escalation clinical trial (ClinicalTrials.gov Identifier: NCT01613118) to evaluate the safety and effectiveness of RE-021, the investigational drug, for primary FSGS treatment. The compound is a first-in-class, orally-active, dual-agent with both angiotensin II (Type I) receptor blocker (ARB) and an endothelin receptor subtype A (ETA) blocker activity. The highly selective, dual antagonist actions of the compound have been demonstrated in in vitro binding assays; similar compounds have been shown to reduce proteinuria in patients with nephrotic syndrome. Division of Pediatric Nephrology at Stony Brook plays an active role in Assessment of Worldwide AKI in Pediatrics, Renal Angina and Epidemiology (AWARE); ClinicalTrials.gov Identifier: NCT01987921, examining whether early kidney injury signs will predict severe subsequent AKI in critically ill children and if the incorporation of urinary biomarkers into the renal angina scoring system will improve the prediction of the severe injury. Stony Brook's Pediatric Nephrology Division plays an active part in the the Midwest Pediatric Nephrology Consortium, collaborating on clinical trials in nephrotic syndrome, hypertension, chronic kidney disease and transplantation. In addition for number of years now they are part of the North American Pediatric Renal Transplant Corporative Study (NAPTRCS), which is creating a North American database on patients with kidney disease, patients undergoing dialysis, and patients who have received transplants.
Advances and Recognitions
Definitions Hypertension - Also known as high blood pressure, hypertension occurs when the force of the blood flow is too high, stretching the tissue that makes up the walls of arteries beyond its healthy limit. This can often lead to heart attack and heart failure, stroke, kidney failure, and other health consequences.
Dialysis - A process for removing waste products and water from the blood when the kidney is no longer able to perform its functions.
Hematuria - The presence of blood in the urine. Blood that you can see is called gross hematuria. Urinary blood that's visible only under a microscope is known as microscopic hematuria and is uncovered after a urine test.
Hydronephrosis - Typically occurring with another disease, hydronephrosis is a condition in which the kidney swells, due to a backup of urine.
Kidney cysts - A cyst is a closed pocket or pouch of tissue filled with fluid or air that can form anywhere in the body. Cysts that form on the kidneys usually contain fluid. One or more cysts may develop on small tubes in the kidneys. The simple kidney cyst is different from the cysts that develop when a person has polycystic kidney disease, which is a genetic disease
Kidney disease - Kidney disease is a condition, most often caused by diabetes or high blood pressure, in which the small blood vessels in the kidneys are damaged, making the kidneys unable to do their job. Waste then builds up in the blood, harming the body.
Proteinuria - Also called albuminuria or urine albumin, proteinuria is an abnormally high amount of protein in the urine. It occurs when proteins from the blood leak into the urine when the filters of the kidney, called glomeruli, are damaged. Proteinuria is a sign of chronic kidney disease (CKD), which can result from diabetes, high blood pressure, and diseases that cause inflammation in the kidney
Transplantation - A kidney transplant is a surgical procedure that replaces a diseased kidney or kidneys with a healthy kidney. The transplanted kidney takes over the work of the kidneys that have failed, eliminating the need for dialysis.